Our Services

From Scientific Questions to Practical Strategy

Roper Toxicology Consulting Limited provides independent, senior-level scientific advice to organizations addressing complex questions in toxicology, product safety, regulatory science, and the development and application of New Approach Methods (NAMs).

Discuss Your Scientific Challenge

Scientific Toxicology Expertise for Complex Decisions

Toxicology challenges rarely exist in isolation. A study design decision may affect a regulatory submission. The selection of an experimental model may determine whether data is accepted and trusted. An innovative emerging technology may appear promising but still require careful evaluation before it is fit for purpose.

Roper Toxicology Consulting Limited helps organizations evaluate these challenges in context.

Whether the starting point is a specific technical question or a broader challenge, the objective is the same: to understand the scientific, regulatory, and business decisions to be made. Available evidence is critically reviewed, uncertainties are identified and practical options are developed. The outcome is a scientifically defensible strategy that helps organizations move forward with confidence.

Regulatory & Scientific Consulting Services

Complex scientific and regulatory decisions require evidence that is relevant, reliable, fit-for-purpose, along with a clear understanding of how the evidence will be used. Roper TCL provides independent scientific and regulatory advice, helping organisations evaluate options, understand uncertainty, and develop scientifically defensible strategies aligned with their objectives. Support may include critical review of existing data, identification of evidence gaps, evaluation of testing strategies, assessment of technology suitability, and selection of scientifically appropriate models and study approaches.

Organ-on-a-Chip and NAMs Services

New Approach Methodologies can provide mechanistically informative and human-relevant evidence when applied within an appropriate scientific and regulatory context. However, a technology should not be selected simply because it is new or because it avoids the use of animals.

Roper TCL supports organizations developing, evaluating, selecting, and implementing organ-on-a-chip platforms, micro-physiological systems, organoids, complex in vitro models, and other NAMs. This includes considering biological relevance, model performance, reproducibility, validation or qualification requirements, regulatory context, and the intended Context of Use.

Core In Vitro Toxicology Speciality Services

Roper TCL provides clients with in vitro toxicology expertise in dermal absorption, skin toxicology, respiratory and inhalation toxicology, and complex in vitro model systems. Support can range from focused advice on an individual study to a broader scientific strategy, including method selection, protocol and study-design review, data interpretation, laboratory or partner identification, and the evaluation of model performance and relevance. Drawing on decades of hands-on scientific and leadership experience, Clive helps clients understand not only how a method works, but whether it is appropriate for the test article, endpoint, and decision it is intended to support.

Scientific Leadership, Training, and Mentoring Services

Strong science depends on knowledgeable, confident people who understand not only what to do, but why they are doing it. Roper TCL provides tailored training, workshops, and mentoring for scientists, scientific leaders, laboratory teams, and organizations seeking to strengthen their capabilities in toxicology, in vitro methods, NAMs, study design, scientific communication, and related areas. Programs are developed around the participants’ experience, responsibilities, and objectives. Support can range from a focused technical session to longer-term mentoring and team-development initiatives designed to build knowledge that remains within the organization.

If you are addressing a complex toxicology question, evaluating a technology, developing a testing strategy, or preparing for an important scientific or regulatory decision, Roper TCL would be pleased to discuss your requirements.

Discuss Your Scientific Challenge

Independent Advice, Directly from an Experienced Toxicologist

The Roper TCL Framework

Roper TCL is a director-led consultancy. Clients work directly with Clive throughout the engagement rather than having a project transferred to a less experienced team after the initial discussion.

This model provides continuity, accountability, and direct access to senior scientific judgement. It also allows Roper TCL to remain flexible, responding to the scope and urgency of each project without imposing a predetermined consulting process.

Where additional expertise is needed, Clive can draw on an international network of trusted scientific, regulatory, technology, and laboratory specialists. The objective is always to assemble the right expertise for the challenge not to make the challenge fit the available service.

The Roper TCL Approach

Understand the Question. An engagement begins with a discussion of the scientific problem, the decisions that need to be made, and the wider regulatory or business context
Evaluate the Evidence. Roper TCL critically evaluates the available data, methods, assumptions, and relevant scientific or regulatory information to identify strengths, limitations, uncertainties, and important evidence gaps.
Define the Strategy. Recommendations are developed around the intended application, available evidence, regulatory context, practical constraints, and the level of confidence required for decision-making.
Support Implementation. Where needed, Roper TCL remains involved during implementation, helping clients evaluate results, address emerging questions, coordinate partners, and refine the approach as the project progresses.

The result is independent scientific advice that is robust, transparent, and practical to implement.

Who We Work With

Roper TCL works with organizations of different sizes and at different stages of development, including:

Pharmaceutical and biotechnology companies
Chemical and crop-protection organizations
Consumer-product and cosmetic companies
Contract research organizations and testing laboratories
Developers of in vitro models, organ-on-a-chip systems, and other scientific technologies
Universities, research groups, and collaborative initiatives
Investors and organizations evaluating scientific technologies or opportunities

Whether the client is an emerging company seeking direction or an established organization requiring specialist independent advice, support is tailored to the specific challenge rather than drawn from a standard package.