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  • Clive Roper

Bite Sized Cool Technologies - Local Acute Irritation Properties of Captan and Folpet with NAMs


Felix M. Kluxen, Clive S. Roper, Signe M. Jensen, and Claire M. Koenig. Characterizing Local Acute Irritation Properties of Captan and Folpet with New Approach Methods. Applied In Vitro Toxicology. Sep 2022.83-101.http://doi.org/10.1089/aivt.2022.0004


I am so proud to be involved with this publication. This programme of work shows that crop protection products local irritation (skin, eye and lung) can be characterized using non animal models within a regulatory framework. 18 studies were performed and are discussed. Most of the tests were OECD test guideline studies although some were not, but were also well understood methods. Adama should be commended for commissioning this work, but more importantly for publicly sharing the data as a route to high quality, human relevant, toxicology.

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